Increasing prevalence of gastrointestinal disorders augmenting the demand for Proton Pump Inhibitors (PPI)

Proton Pump Inhibitors (PPI) are the common class of drugs for the relief of mild gastroesophageal reflux disease and heartburn. They work by temporarily blocking the site of stomach acid secretion in the parietal muscle of the esophagus. PPI's are usually prescribed by a doctor who assesses the severity of the acid problem and will prescribe PPI's that are effective and safe for patients. Proton pump inhibitor drugs are available to buy over the counter without a prescription.

Proton pump inhibitors are sometimes used to replace more long term treatment like antacids, beta-blockers, or proton pump inhibitors that are not successful in treating acid reflux. They can be used as an adjunct to traditional treatment and have been recommended for people with GERD, acid reflux, and heartburn problems. However, their long-term use has not been fully assessed.

The growing prevalence of various gastrointestinal disorders such as hyperacidity is driving the market growth of Proton Pump Inhibitors. According to the National Health Interview Survey 2018, 14.8 million adults were diagnosed with ulcers and 5.9% of adults were diagnosed with ulcers. The growing prevalence of obesity in adults and adolescents is another major factor that is increasing cases of gastroesophageal reflux disease. According to the Hindawi, Obesity is primary among the medical disorders composing metabolic syndrome and is associated with many gastrointestinal diseases.

From the geographical point of view, North America is expected to gain significant growth over the forecast period and this is attributed to high presence of the obese population in the region. According to the National Center for Chronic Disease Prevention and Health Promotion, the prevalence of obesity was 42.4% in 2017~2018. From 1999–2000 through 2017–2018, the prevalence of obesity increased from 30.5% to 42.4%, and the prevalence of severe obesity increased from 4.7% to 9.2%.

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